Protocols for the use of Cyproterone, Medroxyprogesterone and Leuprolide in the Treatment of Paraphilia


Objective: To propose a protocol for minimizing medical complications associated with the use of cyproterone, medroxyprogesterone, and depot leuprolide to treat paraphilia.

Method: Review of the relevant literature.

Results: Certain patient populations should not be treated with these medications, and medical complications associated with each can be detected early and avoided.

Conclusions: For each drug, a series of screening tests prior to use and scheduled testing during use can minimize potential medicual complications.

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